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Addressing these gaps requires focused safety studies that prospectively track headache characteristics and control for baseline headache frequency, medication use and cosupplementation

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Highly invasive triple-negative MDA-MB-231 cells respond to 15 dyn/cm by increasing their migration velocity, whereas normal MCF-10 A epithelial cells and less aggressive triple-negative MDA-MB-468 breast cancer cells show only slight or no increase in motility under the same conditions, respectively [226]

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