Wang, Z., Li, Y., Liao, W., Huang, J., Liu, Y., Li, Z., & Tang, J
Nitrites (NO 2 ) and nitrates (NO 3 ), as representatives of reactive nitrogen species (RNS), affect pH and redox balance through nitration and oxidative inactivation of critical biomolecules (mainly redox-sensitive enzymes) 12,15
Coenzyme Q10 levels decline with age, reducing the skins natural repair ability
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In the trials not every participant advanced to the full 2.4 mg of each component, and dose flexibility was built into the design the target is reached gradually and not universally, so this is reference data describing the trial schedule, not a fixed prescription
Many of these nutritional migraine triggers have vasoactive properties (causes constriction or dilation of blood vessels)(Gallagher 2012), which is why they may contribute to migraine attacks