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They signal fibroblasts to make more collagen and elastin

The same Maquart group documented GHK-Cu-driven increases in dermatan sulfate, chondroitin sulfate, and the small proteoglycan decorin, all of which contribute to dermal hydration and structural organization 5

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10.3389/fimmu.2018.00675 Front Immunol

Topical copper peptides like GHK-Cu are proven to help with barrier repair and skin healing only

During a period of caloric deficit, when circulation may be a limiting factor for peripheral tissue repair, this matters