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Both short- and long-acting GLP-1RAs such as exenatide, lixisenatide and liraglutide were shown to effectively cross the bloodbrain barrier (BBB) [39,40,41]

A Video Clip below on the barriers of a woman scientist to push Novo Nordisk to develop GLP-1 for obesity

This low-dose approach turns the drug into a manageable background aid rather than a dominant physiological force

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