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The released Fe 3+ exhausted intracellular GSH via Fenton reaction, boosting ROS production by TCPP-mediated PDT (Figures 2B, C)
Studies with genetically encoded sensors for Ca 2+ cycling and SV exocytosis revealed the core roles of mitochondria in presynaptic Ca 2+ clearance [54, 55]
m6A-methylated Lonp1 drives mitochondrial proteostasis stress to induce testicular pyroptosis upon environmental cadmium exposure
Patients should be aware that food supplements are not subject to the same rigorous regulatory approval process as medicines, and efficacy claims may not be supported by robust clinical evidence
Future iterations may be weekly oral tablets instead of daily dosing
The use of two complementary peptides enables more complex experimental analysis compared to single-compound models
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