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Our evidences suggested that impaired mitophagy may be a cause of cardiac hypertrophy induced by pressure overload, and semaglutide ameliorated the cardiac hypertrophy by improving mitophagy to suppress the activation of NLRP3 inflammasome (Fig

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By extrapolation and in contrast to treatment with metformin or thiazolidine no laboratory safety monitoring is required when treatment with acarbose is initiated