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It has been suggested that both innate and adaptive immune responses play a role in NCWS [37], and may share some triggers with FM [35]

The underlying mechanisms have not been fully delineated but are likely to involve modulation of the brain dopamine reward system via GLP-1 receptors, which are present both in the ventral tegmental areas (VTA), where dopamine neurons are located, and in the nucleus accumbens (NAc), which is the main projection of VTA dopamine neurons 14

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Those taking anticoagulant medications should exercise caution, as BPC-157 may influence bleeding parameters