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Without biomarker context, supplementation may represent unnecessary expense and potential metabolic interference rather than targeted intervention

All doses caused hyperactivity and decreased weight gain in the dams

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BSO reduces GSH pools to below 1% in many cell types 25,26 and is generally well tolerated, including in studies on other intracellular bacteria where it was used at millimolar concentrations 15,17

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* Average of entire study group (treatment and control)