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doi:10.1016/s0142-9612(03)00331-4 131

The basal-like subtype, commonly referred to as triple negative, lacks ER, PR, and HER2 expression, accounts for approximately 15% of breast cancers, and is associated with poor prognosis (137139) HER2-enriched tumours display high HER2 expression, increased proliferation, and are typically ER- and PR-negative ( Figure 5 ) (135, 140, 141)

doi: 10.1111/bph.14881 212 Gordin-VlezWJChouhanDEspaaRAChenHIBurdickJADudaJEet al

These promising results place ALCAR as an attractive supplement to be explored for prevention approaches

Peptides also affect other hormones that control hunger and fat storage

Crosstalk between FXR and TGR5 controls glucagon-like peptide 1 secretion to maintain glycemic homeostasis