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Autophagy regulates TGF- expression and suppresses kidney fibrosis induced by unilateral ureteral obstruction

Some individuals may require higher doses or have other metabolic factors interfering

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These findings are of great importance for the development of new therapeutic strategies for various diseases related to oxidative stress

1 Introduction Diabetic kidney disease (DKD) is a chronic kidney disorder that has become one of the most devastating complications of diabetes worldwide and a leading cause of end-stage renal failure