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Most of the foundational research was conducted in the 1970s and 1980s, largely in animal models

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This can be an option for patients not responding to medical therapy, women with a large tumor who wish to be pregnant, or for stubborn tumors not responding to the medication Cabergoline

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Most patients require continued therapy to maintain weight loss and counteract metabolic adaptations that promote regain

While there are no strict rules about changing dosages for everyone, there are specific situations where adjustments might be needed