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For a drug to be approved for the pregnant population, it must go through rigorous testing with that population, and that has not yet happened for semaglutide or other GLP-1 (glucagon-like peptide 1) agonists, says Carrie Burns , MD, a board-certified endocrinologist and director of diabetes in pregnancy at Penn Medicine in Philadelphia
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While liraglutide also showed cardiovascular benefit (13% reduction in the LEADER trial), semaglutides evidence is more recent, more robust, and specifically applicable to patients with obesity
(See the blog.) A systematic review found that these drugs might be helpful in intracranial hypertension, a condition that appears to be widespread in these diseases
For joint and tendon concerns, BPC-157 is frequently discussed
doi: 10.1017/S0007114509991747
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