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Initiators of semaglutide (HR, 0.58 [95% CI, 0.51-0.65]) and tirzepatide (HR, 0.42 [95% CI, 0.31-0.57]) had substantially lower risk of the primary end point compared with sitagliptin

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Creatine enhances muscle cell regeneration of ATP, the body's main source of energy

The researchers termed this "chronic cytoprotection." The cell-protection effect did not diminish with extended use

The hospitalization rate was notably high (89.8%), and fatal outcomes were observed in 2.1% of the reported cases (Faillie, et al., 2014)