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PMID 19832808

Mice lacking SAPAP3 groom themselves compulsively to the point of hair loss and skin lesions a striking animal parallel to trichotillomania and the behavior eases when the synaptic defect is corrected

Activities were measured in the presence of glycylglycine as a -glutamyl acceptor substrate

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4) Metabolic enzymes exhibit substrate specificity (e.g., fluvastatin is a substrate of CYP2C9, but not CYP3A4)