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Bacillota mainly include the family Veillonellaceae , the genus Streptococcus and Granulicatella , while Pseudomonadota includes Neisseria and Haemophilus

Metformin primarily reduces glucose production in the liver and increases insulin sensitivity

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4.5 Reduction of TMAO and bile acid metabolism Trimethylamine-N-oxide (TMAO), a pro-atherogenic metabolite produced by the microbial metabolism of dietary choline and carnitine, is reduced in circulation by probiotics through the suppression of TMA-producing microorganisms

The diet was analyzed in terms of the amount of energy, protein, carbohydrates, and fat consumed

Results develop gradually, with most patients noticing visible improvements after 46 sessions