In contrast, there were no significant differences in plasma GLP-1 levels between cocaine-experienced rats and yoked-saline controls after prolonged withdrawal (i.e., extinction day 7) (Fig 1D)
References: GLP1 Receptor Agonists-Effects Beyond Obesity and Diabetes
[DOI] [PMC free article] [PubMed] [Google Scholar] 252.Urbani G., Rondini E., Distrutti E., Marchian S., Biagioli M., Fiorucci S
Food and Drug Administration and is not approved for use as a drug or dietary ingredient
Timeline of the coverage reversal The announcements clustered in the second half of 2025
observed in Nature Medicine , NNMT inhibition in adipose tissue produced favorable body composition changes without negatively impacting muscle mass (Kraus et al., Nature Medicine )