In the event of prolonged treatment, the reduction of stomach acidity by these drugs may reduce the digestive absorption of vitamin B12
Copper peptides do not act on G-protein coupled receptors like GLP-1 agonists, so downregulation is theoretically less likely
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These alternatives must pass through the digestive system, which reduces potency
Similarly, women who are breastfeeding should avoid NAD+ injections, since it is unknown whether the exogenous NAD+ could affect the nursing infant or alter milk composition
While clinical trials in humans are still limited, preclinical studies, veterinary applications, and underground user reports highlight several consistent effects