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The main adverse effects described in clinical trials employing tirzepatide were gastrointestinal, such as nausea, diarrhea, decreased appetite, delayed gastric emptying, vomiting, acid reflux, and constipation (57)

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How to Get a Prescription for a GLP-1 Because GLP-1s are not currently FDA-approved for addiction treatment, clinicians may be hesitant to prescribe the medication for an off-label use