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This study assembled a set of 91 natively unfolded proteins (i.e., IDPs with extended disorder, such as native coils and native pre-molten globules), which at physiological conditions have been reported to have the NMR chemical shifts of a random-coil, and/or lack significant ordered secondary structure (as determined by CD or FTIR), and/or show hydrodynamic dimensions close to those typical of an unfolded polypeptide chain (Uversky et al., 2000a)

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Exosomes have been shown in early research to protect the arthritic joint by promoting cartilage repair, inhibiting inflammation of the joint lining, and helping the bone around your joints stay strong (subchondral bone remodelling)

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