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The combined cardiovascular, metabolic, and gastrointestinal effects require proactive tracking to catch problems early

The SURPASS program (multiple trials, NEJM and Lancet 2021 to 2022) supports the Mounjaro diabetes label

Induced tolerance of Sclerotinia sclerotiorum to isothiocyanates and toxic volatiles from Brassica species

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The drug is primarily metabolized through proteolytic degradation and does not undergo hepatic cytochrome P450 metabolism, which significantly reduces the potential for drug-drug interactions with medications metabolized through these pathways

Try not to use them long-term