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Cautionary Statement Regarding Forward-Looking Statements This press release contains forward-looking statements (as that term is defined in the Private Securities Litigation Reform Act of 1995) about retatrutide as a potential treatment for adults with type 2 diabetes and obesity or overweight and adults with severe obesity and established cardiovascular disease, and the timeline for future readouts, presentations and other milestones relating to retatrutide and its clinical trials and reflects Lilly's current beliefs and expectations

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Research into glucagons metabolic role has long established its capacity to stimulate hepatic glycogenolysis and gluconeogenesis, but more recent work highlights its effects on lipid metabolism and thermogenesis