Research suggests 1-2mg per day injected subcutaneously or intramuscularly produces comparable results to the three-times-weekly approach
Vitamin B12 is not a substitute for folic acid and since it might improve folic acid deficient megaloblastic anemia, indiscriminate use of vitamin B12 could mask the true diagnosis
Huang, T., Zhang, K., Sun, L., Xue, X., Zhang, C., Shu, Z., Mu, N., Gu, J., Zhang, W., Wang, Y., Zhang, Y., & Zhang, W
Pickart L, Thaler MM
The heterodimers stimulate the transcription of the targeted genes by binding to sequence-specific PPAR response elements (PPREs) (Berger and Moller 2002)
However, it is not proven if this actually leads to better results in humans