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10.1038/s41598-024-69165-1 Sci Rep

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while in females, the vulva is the chief site of these macules The presence of numerous melanotic macules on the body may be associated with a variety of syndromes including Carney complex, Peutz-Jeghers syndrome, and LEOPARD syndrome

That means while current data is encouraging, research is ongoing, and doctors remain cautious but optimistic

Ogrodnik, M., et al

Taking more than the recommended dose of certain products over long periods including those that contain iron or fat-soluble vitamins such as vitamins A, D, E, and K may also lead to very serious side effects