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Chloroquine reverses chemoresistance via upregulation of p21(WAF1/CIP1) and autophagy inhibition in ovarian cancer
At present, several studies have shown that patients with neurodegenerative diseases have some common pathological characteristics in the early stage of the disease: pathological protein aggregation and mitochondrial damage or mitochondrial dysfunction in vulnerable brain regions (Klemmensen et al., 2024
This lack of efficacy may be attributed to the low plasma and sputum concentrations of NTZ and the high plasma protein binding of tizoxanide, the active metabolite of NTZ [80], highlighting the need for further pharmacokinetic optimization and clinical research to better understand its potential role in TB treatment
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Free Radic Biol Med 2017;106:1117 [DOI] [PMC free article] [PubMed] [Google Scholar] 46.Sun J, Wen Y, Zhou Y, Jiang Y, Chen Y, Zhang H, Guan L, Yao X, Huang M, Bi H.p53 attenuates acetaminophen-induced hepatotoxicity by regulating drug-metabolizing enzymes and transporter expression
Glutathione helps keep your heart healthy by lowering inflammation, improving blood flow, and reducing the risk of artery blockages
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