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The IR, IGF-1R and their hybrid receptors are expressed by most human tumors, whereby predominant expression of the IR-A isoform correlates with a poor differentiation grade

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Quick Answer: GHRP-2, GHRP-6, hexarelin, and ipamorelin are all synthetic GHS-R1a agonists that stimulate pulsatile growth hormone secretion, but they differ substantially in potency, receptor selectivity, cortisol co-stimulation, and secondary tissue effects differences that determine which compound researchers select for a given model