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The importance of vitamin B12 in adult health is huge

June 27, 2026 The global nutraceutical industry faces a critical

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doi: 10.1097/01.prs.0000222526.21512.4c

Figure 2 However, significant heterogeneity in EPA/DHA dosing (0.53 g/d) and ratios across studies, short trial durations (typically 6 months), and a lack of robust structural outcome data (e.g., joint space narrowing) have precluded their formal recommendation as a standard adjunctive treatment in clinical guidelines (44)