Regarding expression and activity, the knowledge about the regulation of carriers and enzymes that modulate -oxidation in cancer cells is of extreme interest since their inhibition may significantly affect the tumorigenic potential even in the presence of compensatory metabolic pathways
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Hypervitaminosis and toxicity often occur in the context of supplemental misuse or high consumption of food containing lots of preformed vitamin A such as liver or eggs, causing rather mild symptoms such as loose stools, headache, nausea and vomiting, but these side effects occur fairly rarely and usually stop in close proximity to discontinuation [73, 85, 92]
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