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(2022) competitively binds the CoQ binding site of SQOR

Most marketed "drops" claim sublingual or buccal absorption, but there is little peer-reviewed evidence that offlabel compounded drops deliver consistent, therapeutic blood levels

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Weekly injections of B12 over 24 weeks significantly improved neurological disability in patients with MS in a randomized controlled experiment, showing improvements after two weeks of treatment, which were further improved by the addition of lofepramine and l-phenylalanine [137]