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They are known to reduce amyloid-beta accumulation, suppress tau hyperphosphorylation, improve cerebrovascular integrity, and lower systemic inflammation. These effects are not only theoretical

Multiple sequence alignment Protein sequences corresponding to NCBI accession numbers NP_055847.1, NP_780519.3, XP_015133327.2, NP_001107500.1, and XP_005635530.1 were retrieved from the NCBI Protein database

On the NHS, Wegovy is typically prescribed within specialist weight management services according to NICE guidance (TA875), which has stricter eligibility criteria than the marketing authorisation (for most adults, BMI 35 kg/m with a weight-related comorbidity, with adjustments for certain groups)

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