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Tirzepatide Tirzepatide is a dual agonist, meaning it acts as both a GLP-1 and GIP receptor agonist

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On the assessment of adverse drug reactions from spontaneous reporting systems: the influence of under-reporting on odds ratios

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In the SUSTAIN-6 study, which compared subcutaneous semaglutide to placebo, DR complications occurred in 3% of semaglutide and 1.8% of placebo subjects

Sometimes the issue is caloric creep, gradual increases in portion sizes or snack frequency that accumulate without being noticed