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(4) Struktur-Aktivitaets-Studien zur Evaluierung der Bedeutung der C20-Acylierung fuer die pharmakokinetischen Eigenschaften

Phase 2 data published in the New England Journal of Medicine showed mean body weight reductions of up to 24.2% at the highest dose tested over 48 weeks [8]

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Melatonin as a neuroprotective agent was also recommended in those pathologies involving white matter damage 96,97