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Worth stating upfront: this article compares the pharmacology and evidence base of the two routes

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The compound often falls into a gray area, sometimes classified as a dietary supplement, which is subject to less stringent regulations than pharmaceutical drugs

Moderate antioxidant supplementation has no effect on biomarkers of oxidant damage in healthy men with low fruit and vegetable intakes

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In that sense, if 5-amino-1MQ had effects on the same molecular pathways as exercise, aged mice treated with the compound that also exercised would not receive much of an effect from the treatment