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10.1007/s10517-017-3876-x [DOI] [PubMed] [Google Scholar] Khavinson V, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B (2020) AEDG peptide (epitalon) stimulates gene expression and protein synthesis during neurogenesis: possible epigenetic mechanism
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PMCID: PMC10885928
Unit: Dual-chamber Snap Pen (lyophilized peptide + bacteriostatic diluent separated)
Efficacy was evaluated in CADENZA (NCT03386513), a multicenter, open-label, single-arm clinical trial that included adult patients with treatment-nave BPDCN (n = 33) or relapsed or refractory BPDCN (n = 51) without evidence of active central nervous system disease
Beyond sequence, epigenetic evidence points to an NNMT-linked signature in human adipose tissue, indicating the pathway is dynamically active in human fat biology, not only in laboratory animals
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