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Moreover, increased pressure has been shown to enhance cancer cell migration and resistance to the anticancer drug doxorubicin by upregulating the water channel aquaporin 1 [52] and the efflux transporter ABCC1 [53], respectively

So, when single dose pharmacokinetics are studied, the half-life of a drug is ideally determined after intravenous (iv) administration of the drug

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Age-related increase of tumor susceptibility is associated with myeloid-derived suppressor cell mediated suppression of T cell cytotoxicity in recombinant inbred BXD12 mice

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