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Since there are obvious differences between rodent and human physiology, it cannot be ignored that this may have a significant impact on the efficacy and safety of (any) novel agents

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NO-mediated LTP has been implicated in hippocampal learning tasks, including explicit object recognition (Pitsikas, 2015) and spatial learning in Barnes maze and Morris water maze tasks (Majlessi et al., 2008)

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Biol., vol