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In many cases, those patients lab valuesin particular, hemoglobin A1c (HbA1c)dont reflect the uncontrolled diabetes required to justify coverage for GLP-1 receptor agonist treatment

4.2 Systemic mechanism-of-action Systemic interventions have traditionally faced significant challenges due to the nature of the BBB and the complex immune dynamics of the brain

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These intakes complement endogenous synthesis but may be insufficient for certain profiles