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When stacking, many clinicians reduce each peptide by 2550 % from its standalone dose because of the additive effect

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doi:10.1046/j.1523-1747.2000.00166.x

DSIP exhibits analgesic properties for chronic pain conditions, neuroprotective effects through antioxidant mechanisms, and geroprotective actions including 2.6-fold reduction in spontaneous tumor incidence in long-term studies

Mechanistically it is described as neurotrophic, meant to mimic the bodys own nerve-growth factors, the proteins named BDNF, NGF, GDNF, and CNTF that keep neurons alive and wire them together, and to support the survival of cells and the formation of connections

Park S, Park SK (2022) Anti-oxidant and anti-aging effects of phlorizin are mediated by DAF-16-induced stress response and autophagy in Caenorhabditis elegans