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Immun Ageing: I A

Available at: Last accessed: November 2023

A cation exchange chromatography process for purifying a GLP-1 peptide from a mixture comprising said peptide and related or unrelated impurities, comprising the step of: separating said GLP-1 peptide and said related or unrelated impurities of said mixture by elution in a solution consisting essentially of an organic modifier, water, optionally a salt component, and optionally a buffer, with a linear or step gradient or isocratically in salt component and/or with a linear or step pH-gradient or at a constant pH-value, wherein the pH-gradient or pH-value should be in the range where said peptide has a positive local or overall net charge different from the local or overall positive net charge of said related or unrelated impurities so as to remove said related or unrelated impurities

From a cost perspective, 10mg vials typically offer better value per milligram than two separate 5mg vials

Notify me when it lands from 89 / month weekly injection 1 July 2026 Sources: MHRA registers & manufacturer disclosures estimates may change Get first access to oral GLP-1 treatment Waitlist members get the earliest route to tablets and the best terms when they launch

GLP-1 receptor activation also decreases inflammation and fibrosis in the liver through suppressing the release of inflammatory cytokines and dampening inflammasome activation