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Pharmacokinetics, pharmacodynamics and safety of single, oral doses of GSK1278863, a novel HIF-prolyl hydroxylase inhibitor, in healthy Japanese and Caucasian subjects

During bacterial infection, autophagy can be activated by a variety of host factors and pathways, including the formation of autophagosomes around the targeted bacteria and then transferring these pathogens to lysosomes for further degradation (Sparrer et al., 2017)

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