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Haass, C

Notably, the adverse effects caused by metformin therapy for adolescent patients with PCOS, especially gastrointestinal side effects, need to be a concern, as they may affect their quality of life and treatment adherence

Free radicals are unstable molecules that occur naturally but that also enter our bodies through toxins in food, air, water, and even medications

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Indeed, the last three rows of Table 5 show that the up-regulation of CBS has exactly this effect and that the addition of oxidative stress makes the effect much stronger