Chronic conditions that generate persistent oxidative stress, such as liver disease or metabolic disorders, consume glutathione faster
A new mtDNA mutation in the tRNA(Lys) gene associated with myoclonic epilepsy and ragged-red fibers (MERRF) Am
The turning point came around 2015, when higher-dose liraglutide, under the brand name Saxenda, was approved for obesity, confirming the weight loss effect wasnt just a side effect, but a primary therapeutic action. GLP-1s worked differently from earlier diet drugs
Functional lipidomics of oxidized products from polyunsaturated fatty acids
M.WoesteS.HacheneyI.et al (2022)
This cascade leads to increased protein synthesis, cell proliferation, and glucose uptake