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These studies covered a wide range of altitudes, exposure durations, and physiological variables related to AMS and oxidative stress (Figure 2)

& Benedetti, A

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[27] [28] The result is a reduced lipoylation degree of important mitochondrial enzymes, such as pyruvate dehydrogenase complex (PDC) and -ketoglutarate dehydrogenase complex (-KGDHC)

J Thorac Oncol 8(4):502-10, 2013