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Human Peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target

In recent years, the clinical use of glucagon-like peptide-1 (GLP-1) receptor agonists, initially indicated for diabetes and obesity management, has rapidly expanded, with many ongoing investigations into their therapeutic use across a wide range of noncommunicable diseases

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Apart from acetate, an important source of cytosolic acetyl-CoA is by cleavage of citrate that originated from mitochondria, catalyzed by ATP-citrate lyase 264,280,281

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