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doi: 10.1016/j.spen.2020.100835

[4] [5] The lipid improvements with GLP-1 therapy are generally proportional to the degree of weight loss achieved, and individual responses vary considerably

Abstract Background: Metabolic-associated fatty liver disease (MAFLD) is a leading cause of chronic liver disease and is closely linked to type 2 diabetes mellitus (T2DM)

Approximately 90% of GLP-1 is metabolized by DPP-4 before reaching the central venous circulation (Holst and Deacon, 2005), and the peak circulating concentration of active GLP-1 (7-36)NH 2 after a meal in healthy subjects is usually less than 10 pmol/L due to the rapid degradation of DPP-4 ( In order to solve the problem of rapid inactivation of GLP-1 by DPP-4 degradation, GLP-1RAs and DPP-4 inhibitors have been developed to treat T2DM (Kim and Jang, 2015

Picture a healthier, slimmer self

All samples were then centrifuged and tested by HPLC