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Anorectic thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice

Disclaimer: These statements are based on emerging research and are not intended to suggest diagnosis, treatment, or cure

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Although the exact mechanism for this weight-reducing effect is unknown, the proposed mechanism includes alterated perception of taste due to carbonic anhydrase activity and modulation of dopamine and serotonin levels in the brain [241, 244, 245].Empatic has shown promising results in phase 2 clinical trials [241] (Table 2 )

Frhbeck, G., Mndez-Gimnez, L., Fernndez-Formoso, J.-A., Fernndez, S