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Retatrutide is an investigational triple-hormone receptor agonist developed by Eli Lilly that targets three receptors: GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon

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Those with microvascular complications experienced a much larger drop in both glutathione concentrations and synthesis rates compared to healthy controls

Starhof C, Winge K, Heegaard N, Skogstrand K, Friis S, Hejl A