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Two of three subjects who had insulin resistance at baseline showed normal insulin responsiveness at the end of the study, and highly sensitive C-reactive protein (hs-CRP, a marker of systemic inflammation) improved by a median of 25% among participants who showed clinical psoriasis improvement

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Additionally, plant-derived polyphenols (e.g., citrus flavonoids like nobiletin, anthocyanin3Oglucoside) and functional bioactive peptides have demonstrated protective effects in animal studies [162]

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Jang JY, Kim DJ