Injectable bioavailability is approximately 80%, meaning roughly 80% of the injected dose reaches systemic circulation
Regarding clinical outcomes, the analysis showed that participants achieving an optimal response to semaglutide or tirzepatide experienced significant reductions in waist circumference and improvements in insulin sensitivity, changes that paralleled the weight-loss patterns observed across the response groups, indicating clinically meaningful improvements in central adiposity and metabolic health
Values represent means SD from three independent biological replicate experiments
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