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DOI: Published: Publisher Name: Springer, Singapore Print ISBN: 978-981-16-5421-3 Online ISBN: 978-981-16-5422-0 eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences

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Theoretical calculations The geometry of a metal complex was determined using density-functional theory calculations with the Gaussian software package

Major challenges in the field include elucidating the SIRT1 signaling cascade as well as understanding the role of SIRT1 in redox regulation during vascular aging and pathogenesis of CVD