Personalized medical supervision is the key to safe and effective weight loss
By making it more expensive, it just creates a huge hurdle, Offit said
Based upon self-reported data from approximately 12,000 customers subscribed to a comprehensive Hims & Hers weight loss offering, customers report having lost, on average, 10.2 pounds while on compounded GLP-1 injections and 6.3 pounds while on non-GLP-1 compounded oral medication kits, along with a reduced calorie diet and exercise, between their initial weight at consultation and their first check-in approximately 4 weeks later
GLP-1 is produced through the proteolytic cleavage of proglucagon, a protein expressed in the enteroendocrine cells, cells of the pancreas, as well as in the nucleus of the solitary tract (NTS) in the brainstem
IGF-1 LR3 has a significantly extended half-life of approximately 20-30 hours due to reduced binding protein interaction
The trial began in March 2021 and concluded in January 2024, comprising a two-week screening period, a 12-week run-in period, and a 56-week treatment period, followed by a 26-week follow-up period